Roger A Smith Selected Research

PF-06263507

1/2021

ASN004, A 5T4-targeting scFv-Fc Antibody-Drug Conjugate with High Drug-to-Antibody Ratio, Induces Complete and Durable Tumor Regressions in Preclinical Models.

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Roger A Smith Research Topics

Disease

7	Neoplasms (Cancer) 01/2021 - 01/2002
3	Obesity 05/2007 - 01/2005
2	Body Weight (Weight, Body) 05/2007 - 02/2007
2	Renal Cell Carcinoma (Grawitz Tumor) 10/2006 - 01/2006
1	Melanoma (Melanoma, Malignant) 01/2021
1	Margins of Excision 09/2012
1	Hemorrhage 09/2012
1	Rectal Neoplasms (Rectal Cancer) 09/2012
1	Carcinogenesis 01/2006
1	Breast Neoplasms (Breast Cancer) 10/2002
1	Arthritis (Polyarthritis) 06/2002
1	Osteoporosis 06/2002
1	Experimental Arthritis 06/2002

Drug/Important Bio-Agent (IBA)

3	Pharmaceutical PreparationsIBA 01/2021 - 09/2004
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 01/2006
2	Sorafenib (BAY 43-9006)FDA Link 10/2006 - 01/2006
2	raf KinasesIBA 01/2006 - 01/2002
1	PF-06263507IBA 01/2021
1	ASN007IBA 01/2021
1	Ado-Trastuzumab EmtansineIBA 01/2021
1	AntigensIBA 01/2021
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Immunoconjugates (Immunoconjugate)IBA 01/2021
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2021
1	Pain-FreeIBA 09/2012
1	AmidesIBA 05/2007
1	imidazoleIBA 05/2007
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2005
1	RimonabantIBA 01/2005
1	Phosphotransferases (Kinase)IBA 09/2004
1	Gefitinib (Iressa)FDA Link 09/2004
1	Imatinib Mesylate (Gleevec)FDA Link 09/2004
1	Benzofurans (Coumarones)IBA 10/2002
1	p38 Mitogen-Activated Protein KinasesIBA 06/2002
1	CytokinesIBA 06/2002

Therapy/Procedure

3	Therapeutics 02/2007 - 09/2004
1	Proctoscopes (Proctoscope) 09/2012
1	Sutures (Suture) 09/2012